NATURAL PHARMA Group

James J. Sims, Mark S. Donnell, John V. Leary and George H. Lacy + Author Affiliations Department of Plant Pathology, University of California, Riverside, California 92502 ABSTRACT The antimicrobial activity of five compounds extracted from marine algae was tested against Staphylococcus aureus, Salmonella choleraesuis, Mycobacterium smegmatis, Candida albicans, and Escherichia coli. Three of the compounds, cycloeudesmol, laurinterol, and debromolaurinterol, exhibited activity at concentrations approaching that of streptomycin. None of the compounds inhibited all of the organisms tested. There appeared to be selectivity for gram-positive microbes. Copyright © American Society for Microbiology